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Weight Loss and Depression Although weight gain is commonly associated with depression, weight loss can also be a problem. With severe depression, you might lose weight because youve lost your interest in food, which comes from losing in interest in pleasure, Gordon says.

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Best antidepressant for weight loss: Wellbutrin (Bupropion) Although there are older antidepressants that may cause a person to lose weight, most are associated with weight gain with the exception of Wellbutrin. For this reason, if weight is a big concern, I would recommend trying this particular medication before others.

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Cayenne pepper may help kickstart weight loss. But healthy eating and exercise are your best tools for longterm, sustainable weight management. Focus on eating a balanced diet that includes: protein; fruits; vegetables; whole grains; legumes; plant fats; Also, find simple ways to add exercise to your daily routine.